Carboplatin-Induced Hypersensitivity Reaction
نویسندگان
چکیده
منابع مشابه
Carboplatin-Induced Hypersensitivity Reaction
We describe a 65-year-old female with relapsed ovarian cancer who developed a severe hypersensitivity reaction during the second cycle of carboplatin treatment. The patient developed respiratory failure, acute respiratory distress syndrome and hypotension, requiring admission to the intensive care unit.
متن کاملCarboplatin-induced severe hypersensitivity reaction: Role of IgE-dependent basophil activation and FcεRI
Basophil activation was observed in patients with a history of carboplatin-induced severe hypersensitivity reaction (HR). However, the precise mechanism by which carboplatin induces basophil activation and the associated surrogate markers remains to be elucidated. To investigate whether IgE-dependent mechanisms, including the overexpression of FcεRI, participate in carboplatin-induced basophil ...
متن کاملCarboplatin hypersensitivity reactions.
Carboplatin is used widely to treat cancers such as lung, breast, and ovarian. Hypersensitivity reactions (HSRs) to carboplatin can occur, often after numerous doses. The reactions can range from mild to life threatening. Oncology nurses witness the reactions and are instrumental in providing interventions to assist patients. Symptoms include flushing, rashes, itchy palms, nausea, difficulty br...
متن کاملPrasugrel-Induced Hypersensitivity Skin Reaction
We report a case of hypersensitivity skin reaction to prasugrel. The patient exhibited a generalized skin rash after treatment with prasugrel, which was resolved after discontinuation of prasugrel and substitution to clopidogrel. Clopidogrel was successfully administered as an alternative to prasugrel without any signs of further hypersensitivity.
متن کاملHypersensitivity and cross-reactivity to cisplatin and carboplatin.
Cisplatin was the first of the platinum drugs. Second-generation platinum derivative was carboplatin that its efficacy in the treatment of many malignancies is equal to cisplatin, and its toxicity profile is more favorable. Here we report on a 50-year-old woman with a history of cervix cancer who developed a severe hypersensitivity reaction (HSR) to carboplatin. She was admitted to the emergenc...
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ژورنال
عنوان ژورنال: Case Reports in Oncology
سال: 2012
ISSN: 1662-6575
DOI: 10.1159/000337578